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W H I T E  P A P E R


                     aestheticmed.co.uk                                              HAND REVOLUMISATION




























































                  ABSTRACT                                       Conclusion:  PCL injections are a reliable method for hand
                  Background:  Dorsal hand volume loss results in the  volumisation. Results persisted for up to three years in
                  perception of ageing appearance. Several volumising fillers   some patients. Laser vein viewer and cannula delivery
                  have been used for this correction.            ensure uniform injections and avoid intravascular injuries.
                  Objective: To report restoration of dorsal hand volume using
                  cannula delivery of polycaprolactone (PCL) microspheres  INTRODUCTION
                  and to assess efficacy, duration, and safety up to three  Loss of subcutaneous volume in the dorsal hands are a
                  years post-treatment.                          visible sign of ageing, resulting in interphalangeal hollows
                  Method:  15 patients with volume loss of their hands were  and “bony” appearance of the hands. Veins become more
                  evaluated by clinical examination, photography and a hand-  visible with this loss of dorsal hand volume. 1-5  Hands also
                  volume grading scale. PCL was injected by 25G cannula  exhibit ageing as a result of photodamage with loss of
                  after locating dorsal veins using a viewing laser to avoid  skin elasticity, rhytids, skin laxity, and dyspigmentation.
                  intravascular injections. Patients’ satisfaction and grade of   There has been increased use of injectable hyaluronic acid
                  severity were re-evaluated at early (three to six months) and   and  hydroxyapatite  fillers  for  hand  re-volumisation.
                                                                                                           1–6
                  late (12 to 18 months) timepoints following the procedure. A   Polycaprolactone  microsphere  (PCL)  injections  were
                  second treatment was offered if desired by the patient.  introduced in Europe for skin volumising approximately
                  Results: Eight participants required one treatment session   seven years ago. 9
                  to achieve satisfaction. Five had two treatments. Patients   A pilot study of hand volumisation in five patients
                  requiring a second treatment were reassessed after 12  treated  with  PCL  filler  has  been  reported. 10  The PCL
                  months. All patients had improvements on the severity  microspheres are 25–50μm size, suspended in a vehicle of
                  score by the end of the evaluation period. Side effects were   carboxymethylcellulose (CMC), consisting of gel carrier
                  minimal and transient. No patients developed bruising.  and PCL filler. PCL microspheres are smooth, spherical, and



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